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Wednesday, January 18, 2023

PMID: 32717247 DOI: 10.1016/j.urology.2020.07.019 Abstract Objective: To explore associations between dietary habits and erectile dysfunction (ED) in a cohort of patients presenting to a high-volume men's health clinic. Materials and methods: All patients presenting to a high-volume men's health clinic between July 2018 and May 2019 were evaluated for their dietary habits and screened with the International Index of Erectile Function-5 (IIEF-5) and Androgen Deficiency in Aging Males (ADAM). The primary outcome measure was the impact of dietary habits on ED, defined as IIEF-5 <22. Stepwise logistic regressions were used to control for patient characteristics and relevant comorbidities. Results: Two hundred seventy-one patients were included. Primary reasons for visit were ED (110, 40.6%), hypogonadism (39, 14.4%), benign prostatic hyperplasia/lower urinary tract symptoms (80, 29.5%), and Peyronie's Disease (30, 11.1%). 176 (64.9%) followed no diet, while 11 (4.1%), 11 (4.1%), 8 (2.9%), and 11 (4.1%) were whole food only, low-carb/keto, vegetarian/pescatarian, and low-fat, respectively. Additionally, 105 (38.7%) reported organic foods consumption, while 51 (18.8%) had no processed food consumption, and 77 (28.4%) performed intermittent fasting. Patients reporting ED were more likely to be over the age of 65, had higher body mass index, more comorbidities, and less likely to report an organic diet or intermittent fasting. There were no correlations between diet and ADAM score. In adjusted analysis, patients reporting organic diet or intermittent fasting were significantly less likely to have ED. Conclusion: This is the first study suggesting organic diet and intermittent fasting to be protective against ED. These results are hypothesis-generating and warrant further exploration. Copyright © 2020 Elsevier Inc. All rights reserved. Similar articles Is erectile dysfunction a reliable proxy of general male health status? The case for the International Index of Erectile Function-Erectile Function domain. Salonia A, Castagna G, Saccà A, Ferrari M, Capitanio U, Castiglione F, Rocchini L, Briganti A, Rigatti P, Montorsi F. J Sex Med. 2012 Oct;9(10):2708-15. doi: 10.1111/j.1743-6109.2012.02869.x. Epub 2012 Aug 15. PMID: 22897643 Erectile function after prostate brachytherapy. Merrick GS, Butler WM, Wallner KE, Galbreath RW, Anderson RL, Kurko BS, Lief JH, Allen ZA. Int J Radiat Oncol Biol Phys. 2005 Jun 1;62(2):437-47. doi: 10.1016/j.ijrobp.2004.10.001. PMID: 15890585 Should We Tailor the Clinical Management of Erectile Dysfunction According to Different Ages? Capogrosso P, Ventimiglia E, Boeri L, Pozzi E, Chierigo F, Schifano N, Abbate C, Matloob R, Montorsi F, Salonia A. J Sex Med. 2019 Jul;16(7):999-1004. doi: 10.1016/j.jsxm.2019.03.405. Epub 2019 Apr 30. PMID: 31053559 Diet and Men's Sexual Health. La J, Roberts NH, Yafi FA. Sex Med Rev. 2018 Jan;6(1):54-68. doi: 10.1016/j.sxmr.2017.07.004. Epub 2017 Aug 1. PMID: 28778698 Review. New treatment options for erectile dysfunction in patients with diabetes mellitus. Basu A, Ryder RE. Drugs. 2004;64(23):2667-88. doi: 10.2165/00003495-200464230-00004. PMID: 15537369 Review. See all similar articles Cited by The association between plant-based diet and erectile dysfunction in Chinese men. Lu Y, Kang J, Li Z, Wang X, Liu K, Zhou K, Wang W, Shen C. Basic Clin Androl. 2021 May 13;31(1):11. doi: 10.1186/s12610-021-00129-5. PMID: 33980148 Free PMC article. MeSH terms Adult Aged Erectile Dysfunction / diet therapy* Erectile Dysfunction / physiopathology Fasting / physiology* Food, Organic* Humans Male Men's Health Middle Aged Penile Erection / physiology* Treatment Outcome Related information MedGen LinkOut - more resources Full Text Sources ClinicalKey Elsevier Science Medical MedlinePlus Health Information https://pubmed.ncbi.nlm.nih.gov/32717247/